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Name Aga Khan University
Location Pakistan, Pakistan
URL https://www.aku.edu/Pages/home.aspx
Aga Khan University

About University

The Aga Khan University (AKU) is committed to enhancing the quality of life across the developing world and beyond through exceptional teaching, research, and healthcare services. The University's mission focuses on educating students in leadership, both locally and globally, while generating innovative solutions to challenges that impact millions. AKU works to raise aspirations and standards in the countries it serves, promoting the empowerment of women and marginalized groups, supporting pluralism, and collaborating with both local partners and prestigious global organizations to achieve mutual goals. Founded in 1983 as Pakistan's first private university, AKU is a not-for-profit institution and part of the Aga Khan Development Network. Over time, the University expanded its reach, with campuses in Kenya, Tanzania, Uganda, Afghanistan, and the United Kingdom, marking its growth and global impact.

Initially established as a health-sciences university, AKU has become one of the largest private healthcare providers in Pakistan and East Africa. The University's hospitals were the first in these regions to receive accreditation from the U.S.-based Joint Commission International. AKU's research and graduates have shaped health policy and practice at both national and international levels. Over the years, the University has broadened its academic offerings, introducing programs in teacher education, journalism, public policy, early childhood development, and the study of Muslim civilizations. In 2023, AKU launched the Faculty of Arts and Sciences, designed to educate future leaders across various fields. Looking forward, the University plans to establish additional graduate professional schools. As His Highness the Aga Khan, the founder and Chancellor of AKU, stated, the goal is to be at the forefront of both scientific and humanistic knowledge, contributing research and graduates to thriving economies and progressive political systems.

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Medicine Group (1)

Case Report Article ID: igmin228
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Open Access Policy refers to a set of principles and guidelines aimed at providing unrestricted access to scholarly research and literature. It promotes the free availability and unrestricted use of research outputs, enabling researchers, students, and the general public to access, read, download, and distribute scholarly articles without financial or legal barriers. In this response, I will provide you with an overview of the history and latest resolutions related to Open Access Policy.

Levetiracetam-induced Rhabdomyolysis - A Rare Complication
by Ayisha Farooq Khan, Naeemuddin Shaikh, Faryal Abdy and Dureshahwar Kanwar

Background: Levetiracetam is an anti-epileptic drug that works by modulation of synaptic neurotransmitter release through binding to the synaptic vesicle protein 2A. Levetiracetam is generally well tolerated. Common side effects of levetiracetam include lethargy, drowsiness, headaches, and mood changes. Rhabdomyolysis and an increase in Creatine Kinase (CK) levels are one of the rarely reported effects of levetiracetam.Case presentation: We present a case of a 20-year-old patient with previously known epilepsy (non-compliant with medicine) who ...presented with a seizure. The patient was given 1 gram of levetiracetam in the emergency department and was kept at a maintenance dose of 500 mg twice a day. The workup revealed acute kidney injury and raised levels of creatinine kinase that peaked at 19,757 IU/L 72 hours after levetiracetam was started. Levetiracetam was later switched to lamotrigine and aggressive intravenous hydration was done. Gradual improvement of CK level was noted accompanied by improvement in renal function.Conclusion: Only a few cases of levetiracetam-induced rhabdomyolysis have been reported worldwide. Our case report highlights the importance of monitoring creatinine and CK levels while treating patients with levetiracetam as rhabdomyolysis can be asymptomatic with a rise in CK levels only.

Neurology
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