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Abstract

Meng Zhang 編集者 at IgMin Research

私たちの使命は、学際的な対話を促進し、広範な科学領域にわたる知識の進展を加速することです.

Biography

2020.11-now, Principal Investigator, the First Affiliated Hospital, School of Medicine, Zhejiang University
2020.03-2020.09, Research fellow, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
2015.09 – 2020.01, Ph.D., Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, China
2016.01-2016.06, Cooperation in Dr. Jacob Hanna’s lab (Weizmann institute of science, Israel)
2012.09 – 2015.06, M.S., An’hui University, Hefei, China
2008.09 – 2012.06, Bachelor Degree of Biotechnology, He’nan Normal University, Xinxiang, China

Research Interest

Erythroid differentiation of pluripotent stem cells (PSCs) is an important research direction to alleviate the clinical "blood shortage" problem, but the erythroid cells from iPSCs are not mature enough to meet the clinical standards. Our team focus on to optimize the differentiation system from PSCs by screening with small molecular library and Crispr/Cas9 library to solve the problem of poor efficiency of enucleation. We also explore the epigenetic and transcriptional mechanism of terminal erythropoiesis.